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Alimta And Cisplatin For Mesothelioma Treatments
By Eden Alii
The Food and Drugs Administration (FDA) have approved a combination of Alimta and Cisplatin for mesothelioma treatments, and other asbestos-associated diseases. The happens to be the first and only drug that is proved to help treat mesothelioma patients having any asbestos-associated disease approved by the FDA. Alimta was endorsed to be used with cisplatin, which is an approved chemotherapy agent good for malignant mesothelioma treatments, a deadly tumor of the lung lining, in mesothelioma patients who do not want to undergo surgery. One of the most lethal, painful, and devastating cancers a person can have is malignant mesothelioma. There are about 10,000 and 15,000 mesothelioma patients annually diagnosed with malignant mesothelioma in the world, and it increases greatly every year. Several people do not even know that they have malignant mesothelioma until it has gotten to a severe and advanced stage, whereby mesothelioma treatments options of surgery or radiation are not necessary. Alimta/cisplatin have really proven different. There was a comparison of this combination with cisplatin alone with around 448 mesothelioma patients from 19 nations - the biggest trial till date among mesothelioma patients having malignant mesothelioma. The results shown was that the total survival rate was 30% increased (about Alimta/cisplatin was used for 12.1 months compared to 9.3 months for cisplatin alone), and about 50.3% of mesothelioma patients undergoing Alimta/cisplatin treatment lived a year after in comparison to 38.0% who had only cisplatin. It has been proved for the first time that chemotherapy assists mesothelioma patients with malignant mesothelioma extend their lives, which is something to count for. Furthermore, research have also shown that there was an lung functionality

improvement when the Alimto/Cisplatin was used, compared to the use of Cisplatin alone. However, there are some vital safety information. There are hematolgoic and non-hematologic side effects related to the use of Alimta, and they are anaemia, neutropenia, nausea, thrombocytopenia, vomiting, diarrhea, fatigue, pain, and skin rash. In order to decrease the severity of the side effects, all mesothelioma patients using Alimta must take a dose of folic acid and intramuscular injections of vitamin B12 daily.
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What is mesothelioma?
Mesothelioma (pronounced mee-so-thee-lee-oma) is a cancer of the mesothelium. The mesothelium is a thin membrane that lines the chest and abdomen and surrounds the organs in these areas. The lining around the lungs is called the pleura and in the abdomen it is known as the peritoneum. Mesotheliomas are uncommon ...
Pleural mesothelioma
The pleura has two layers: the inner (visceral) layer, which is next to the lung and the outer (parietal) layer, which lines the chest wall. The two layers of the pleura are usually in contact and slide over each other as we breathe. The membranes produce fluid, which allows them ...
Peritoneal mesothelioma
The lining of the abdomen is known as the peritoneum. It also has two layers: the inner (visceral) layer, which is next to the abdominal organs and the outer (parietal) layer, which lines the abdominal wall. If the mesothelioma is in the peritoneum it is called a peritoneal mesothelioma and ...
What causes mesothelioma?
Up to 9 out of 10 cases of mesothelioma are caused by exposure to asbestos. Asbestos is a natural mineral, mined from rock found in many countries. It is made up of tiny fibres that are as strong as steel but can be woven like cotton and are highly resistant ...
What are the symptoms of mesothelioma?
Mesothelioma often starts as many tiny lumps (nodules) in the pleura, which may not show up on scans or x-rays until they are quite large. The main symptoms of pleural mesothelioma are pain in the chest and breathlessness. Some people also notice that their voice becomes hoarse and they have ...
How it is mesothelioma diagnosed?
Most people begin by seeing their GP when they have symptoms. Your GP will examine you and may arrange for you to have some tests or x-rays. You may be referred to hospital for these tests and for specialist advice and treatment. At the hospital the doctor will take your ...
Stages of mesothelioma
The stage of a cancer is a term used to describe its size and whether it has spread beyond its original site. Knowing the extent of the cancer helps the doctors to decide on the most appropriate treatment. A staging system has not yet been established for peritoneal mesothelioma There are ...
Treatment of mesothelioma
The treatment for mesothelioma will depend on whether it is only in one place or has spread. Currently, there is no cure for mesothelioma, unless it can be removed by an operation. Unfortunately, when mesothelioma is diagnosed, it has usually already spread beyond the point where it could be removed ...
Surgery
In the uncommon situation where the cancer is only in one area of the pleura (localised), surgery can be used to treat mesothelioma. It may involve removing part, or all, of the pleura and the lung tissue close to it, which is known as pleurectomy/decortication. Sometimes the pleura, diaphragm and ...
Radiotherapy treatment
Radiotherapy treats cancer by using high-energy x-rays that destroy the cancer cells while doing as little harm as possible to normal cells. As a treatment for mesothelioma, radiotherapy is usually given to help relieve symptoms such as pain and breathlessness, rather than to try to cure the mesothelioma. Often, only ...